Welcome to
Pioneering interdisciplinary research at the intersection of science, technology, and innovation. Dedicated to pushing the boundaries of human knowledge.
Our laboratory focuses on cutting-edge research that bridges fundamental science with real-world applications.
Featured
The decline in spatial memory in adult mice is associated with decreased mitophagy, which affects neurogenesis in the dentate gyrus. Pharmacological enhancement of mitophagy shows therapeutic potential for counteracting age- or disease-related cognitive decline. (CNS Neuroscience & Therapeutics, 2024)
Read more
Gut microbiota from bipolar depression patients induces the development of bipolar depression by modulating aberrant synaptic connectivity and dopamine transmission in the VTA-mPFC pathway. (Molecular Psychiatry, 2025)
Read more
Personalized rTMS targeting the occipital cortex based on OFC-V1 functional connectivity significantly improves depressive symptoms in adolescents and young adults with bipolar disorder, with excellent safety profile. (BMC Medicine, 2026)
Read more
Bipolar depression patients exhibit distinct gut microbiome profiles. Fecal microbiota transplantation from BD patients induces depression-like behaviors in mice, confirming the causal role of gut microbiota in bipolar depression pathophysiology.
Read more
This review integrates neural, humoral, and inflammatory mechanisms linking eye disease to mood dysregulation, while proposing a multidisciplinary framework for screening, treatment, and long-term follow-up in precision mental health care. (Progress in Retinal and Eye Research, 2026)
Read more
Featured
A network meta-analysis of 41 RCTs (n=11,678) ranks metabolic side effects of antipsychotics and mood stabilisers in bipolar disorder, finding antipsychotics more likely to disturb metabolism than mood stabilisers, with distinct drug-specific profiles. (eClinicalMedicine, 2024)
Read moreA diverse group of passionate researchers driving scientific innovation.
We welcome inquiries from prospective students, collaborators, and fellow researchers.
59 Chengzhan Road
Hangzhou
dorhushaohua@zju.edu.cn
0571-87235995